N/A Homes with Three Or More Stories

N/A Homes with Three Or More Stories

Welcome to the enchanting neighborhoods of Missouri, where charm meets modern living in homes that rise above the rest! If you’re searching for spacious and distinctive residences, look no further than our stunning selection of three or more story homes. These architectural gems not only offer ample living space but also provide breathtaking views and a unique lifestyle that is perfect for families, professionals, and anyone in between.

Imagine waking up each morning in a beautifully designed multi-story home, where each level offers its own character and purpose. The first floor typically showcases inviting living spaces, perfect for entertaining guests or enjoying quality family time. Ascend to the second floor and discover cozy bedrooms, each designed for comfort and tranquility. The top levels often feature versatile spaces, such as home offices, playrooms, or even luxurious master suites with panoramic views of the surrounding landscape.

Living in Missouri means enjoying a vibrant community filled with friendly neighbors, local parks, and convenient amenities. Whether you’re exploring the rich history of the area or indulging in the delicious local cuisine, you’ll find that life here is both fulfilling and exciting. The neighborhoods are known for their welcoming atmosphere and a strong sense of community, making it easy to forge lasting connections.

Discover the allure of three or more story homes in Missouri today! With their spacious layouts and unique designs, they offer a perfect blend of comfort and style, making them an ideal choice for your next chapter. Embrace the opportunity to create lasting memories in a home that truly reflects your lifestyle. Your dream home awaits!

Newest N/A Homes with Three Or More Stories

$7,748,800
5 Beds ⋅ 4 Baths ⋅ 26057899 MLS ⋅ ACTIVE Status
Imagine owning a timeless piece of Missouri history. More than 250 years ago, the Osage people traveled these valleys, and pioneers like Daniel Boone, his son Nathan and nephew/adopted son Jonathan Bryan helped shape this remarkable landscape. A captivating driveway leads around to a ONE-OF-A-KIND property built in the 1840’s for Jonathan Bryan. “Bryan Mill” rests gracefully on 105.4+/- acres providing a peaceful & tranquil atmosphere, conveniently located near Augusta & Defiance, with a STRIKING, FINELY DETAILED, FULLY FURNISHED, FRENCH INSPIRED w/exquisite imported antiques curated by Annie Brahler of EuroTrash, Inc. At the heart of the property is an 1840s built cottage exquisitely reimagined as a luxurious country residence, and STATELY early 1800’s built 68’x36’ Stone mill/outbuilding with 2 BEAUTIFUL automatic solid wood doors, floor-to-ceiling Stone fireplace, 37’+/- vaulted ceiling, kitchen, 2 half baths, & an abundant amount of storage space, AND a COMPLETELY REDONE stone chicken coop. Throughout the cottage, historic details have been carefully preserved and complemented by modern mechanical systems, conveniences, and automated security and surveillance. The home boasts 2,815+/- SqFt, 5 bedrooms, 2 full baths, with mostly original hardwood flooring throughout and a kitchen anchored by a 65 inch La Cornue Chateau Series range. The historic mill is equally remarkable. Beautifully restored and fully climate-controlled with modern HVAC systems, the mill features a catering kitchen and expansive event and entertaining spaces. It offers an extraordinary setting for private dinners, celebrations, retreats, creative pursuits, or large-scale entertaining—all without ever leaving the privacy of the estate. Create a legacy where your children and grandchildren can reconnect with nature—plant gardens, raise animals, ride horses, explore miles of side-by-side trails, or simply enjoy the peace and beauty that only a property like this can offer. Beyond the residence, private acreage unfold through rolling fields, mature woods, gardens, and majestic private pathways winding throughout the estate. A dramatic boulder firepit creates an intimate destination for evenings outdoors, while even the custom chicken coop has been thoughtfully designed to complement the architecture and character of the property. Opportunities to own a tract with this combination of history, natural beauty, privacy, and location are exceptionally rare, especially with frontage on the coveted Hwy F. This isn't just land—it's a place where your family's next chapter can begin and memories can be made for generations to come. MUST SEE! Today, you have the rare opportunity to own 105.4+/- acres of beautiful land just off Highway F, conveniently located near Augusta and Defiance, with over $1,000,000 of road and infrastructure improvements completed creating multiple opportunities for building sites on the property with electric, well and septic in place. With breathtaking ridge-top views and rolling countryside, this property is the perfect setting for a private family retreat, a picturesque mini ranch, or private equestrian estate. Create a legacy where your children and grandchildren can reconnect with nature—plant gardens, raise animals, ride horses, explore miles of side-by-side trails, or simply enjoy the peace and beauty that only a property like this can offer. *ALL PARTIES UNDERSTAND PROPERTY IS SUBJECT TO SURVEY AND APPROVED THROUGH CITY & ALL GOVERNMENTAL AUTHORITIES.* Seller will also consider dividing the property in different ways. Acreage sold SEPARATELY. See MLS #’s: 26053202 (LOT #1, 22+/- ACRES), 26053203 (LOT #2, 12.5+/- ACRES), 26053360 (LOT #3, 38.5+/- ACRES), & 26053204 (LOT #4, 32+/- ACRES).

2275 Hwy F, Defiance
$3,450,000
5 Beds ⋅ 4 Baths ⋅ 26053202 MLS ⋅ ACTIVE Status
Imagine owning a timeless piece of Missouri history. More than 250 years ago, the Osage people traveled these valleys, and pioneers like Daniel Boone, his son Nathan and nephew/adopted son Jonathan Bryan helped shape this remarkable landscape. A captivating driveway leads around to a ONE-OF-A-KIND property built in the 1840’s for Jonathan Bryan. “Bryan Mill” rests gracefully on 22+/- acres providing a peaceful & tranquil atmosphere, conveniently located near Augusta & Defiance, with a STRIKING, FINELY DETAILED, FULLY FURNISHED, FRENCH INSPIRED w/exquisite imported antiques curated by Annie Brahler of EuroTrash, Inc. At the heart of the property is an 1840s built cottage exquisitely reimagined as a luxurious country residence, and STATELY early 1800’s built 68’x36’ Stone mill/outbuilding with 2 BEAUTIFUL automatic solid wood doors, floor-to-ceiling Stone fireplace, 37’+/- vaulted ceiling, kitchen, 2 half baths, & an abundant amount of storage space, AND a COMPLETELY REDONE stone chicken coop. Throughout the cottage, historic details have been carefully preserved and complemented by modern mechanical systems, conveniences, and automated security and surveillance. The home boasts 2,815+/- SqFt, 5 bedrooms, 2 full baths, with mostly original hardwood flooring throughout and a kitchen anchored by a 65 inch La Cornue Chateau Series range. The historic mill is equally remarkable. Beautifully restored and fully climate-controlled with modern HVAC systems, the mill features a catering kitchen and expansive event and entertaining spaces. It offers an extraordinary setting for private dinners, celebrations, retreats, creative pursuits, or large-scale entertaining—all without ever leaving the privacy of the estate. Create a legacy where your children and grandchildren can reconnect with nature—plant gardens, raise animals, ride horses, explore miles of side-by-side trails, or simply enjoy the peace and beauty that only a property like this can offer. Beyond the residence, private acreage unfold through rolling fields, mature woods, gardens, and majestic private pathways winding throughout the estate. A dramatic boulder firepit creates an intimate destination for evenings outdoors, while even the custom chicken coop has been thoughtfully designed to complement the architecture and character of the property. Opportunities to own a tract with this combination of history, natural beauty, privacy, and location are exceptionally rare, especially with frontage on the coveted Hwy F. This isn't just land—it's a place where your family's next chapter can begin and memories can be made for generations to come. MUST SEE! *ALL PARTIES UNDERSTAND PROPERTY IS SUBJECT TO SURVEY AND APPROVED THROUGH CITY & ALL GOVERNMENTAL AUTHORITIES.* Additional acreage FOR SALE. See MLS #’s: 26053203 (LOT #2, 12.5+/- ACRES), 26053360 (LOT #3, 38.5+/- ACRES), & 26053204 (LOT #4, 32+/- ACRES).

2275 Hwy F, Unit LOT 1, Defiance
$335,000
3 Beds ⋅ 3 Baths ⋅ 26051053 MLS ⋅ ACTIVE Status
Welcome to a home that feels like a piece of Perryville’s story where timeless craftsmanship, character, and charm come together in a truly special setting. Nestled on nearly a full acre in the heart of the city, this remarkable property offers a rare combination of historic beauty and the space today’s homeowners desire. From the moment you step inside, you’ll be captivated by the beautiful woodwork, intricate trim, stained glass accents, and architectural details that simply cannot be replicated in modern construction. Warm natural light fills the spacious rooms, creating an inviting atmosphere that makes you want to slow down, settle in, and stay awhile. Whether you're hosting friends and family, creating a workshop in the detached garage, enjoying the expansive grounds, or simply appreciating the character found around every corner, this home offers something truly special. Properties with this much history, craftsmanship, land, and presence rarely come available in the heart of Perryville. If you're looking for more than just a house, if you're looking for a home with a story, a soul, and a feeling all its own, you owe it to yourself to see this one in person.

318 E, Perryville
$695,000
3 Beds ⋅ 4 Baths ⋅ 26043689 MLS ⋅ ACTIVE Status
Nestled on 15 partially wooded acres just minutes from Kirksville, Missouri, this stunning home exudes a unique southwest flair. The custom-designed cedar-sided residence showcases meticulous craftsmanship, highlighted by two-story vaulted ceilings that create an inviting atmosphere. Throughout the home, octagonal spaces and wood beams add architectural interest, while an open hand-cut spiral staircase serves as a striking focal point. Inside, the layout features a spacious living area, a private dining room for intimate gatherings, and a dedicated office space, perfect for remote work or study. The high-end kitchen is a culinary enthusiast's dream, boasting maple countertops and top-of-the-line sub-zero appliances, including a built-in refrigerator and freezer. This thoughtful design ensures both functionality and elegance in everyday living. The outdoor spaces are equally impressive, featuring a wraparound deck that provides stunning views of the natural landscape. A shared pond adds a tranquil element, perfect for relaxing or enjoying recreational activities. The property also includes a spacious 3-car garage, offering ample storage and parking options, along with a full unfinished walk-out basement that presents opportunities for customization and expansion. This home is a harmonious blend of luxury and nature, making it an ideal hunting retreat or family residence.

22694 Spencer Ln, Kirksville
$1,425,000
4 Beds ⋅ 4 Baths ⋅ 26019928 MLS ⋅ ACTIVE Status
Designed for both everyday comfort and effortless entertaining, this home showcases rich hardwood flooring, elegant crown molding throughout, and inviting living spaces centered around a warm, cozy fireplace. The beautifully appointed kitchen features stainless steel appliances and durable Super Natural Iron Core flooring, blending style with functionality. The walk-out lower level expands your living options with additional entertaining space and includes a large safe room—ideal for peace of mind and versatility when hosting guests or accommodating extended stays. Equestrian enthusiasts will appreciate the impressive, well-designed facilities, including a 70x80 barn, 48x63 barn with 14x48 and 13x48 lean-tos, an 80x70 enclosed riding arena, and an 80x120 outdoor arena. The property also features a 30x36 mare barn with six runs, five Classic Equine stalls, and a charming she shed—perfectly suited for a fully functional and turnkey horse operation. New roof 2022, more updates in 2023.

3952 Frye Rd, Farmington
$399,000
6 Beds ⋅ 5 Baths ⋅ 26018487 MLS ⋅ ACTIVE UNDER CONTRACT Status
From the moment you arrive, this home makes a statement. Inside, you’ll be captivated by rich original hardwood floors, intricate architectural details, and craftsmanship that simply can’t be replicated today. Every room tells a story—from the grand living spaces to the private library and cozy den—offering both sophistication and warmth. With 6 spacious bedrooms and 5 bathrooms, this home offers incredible flexibility for both everyday living and entertaining. One of its most unique features is the fully functional third floor—designed as a private living space complete with its own large living room, kitchen, and bedrooms. Perfect for in-law quarters, extended family, or private guest accommodations, this space adds an entirely new level of versatility. The primary suite is truly exceptional, featuring a spa-inspired bathroom that feels straight out of a luxury retreat. Enjoy a stunning walk-in tiled shower, dual sink vanity, and an additional dedicated vanity/makeup area with its own mirror—perfect for getting ready with ease. A spacious walk-in closet completes the suite, offering both style and function. Throughout the home, you’ll also find three fireplaces adding charm, character, and cozy ambiance to multiple living spaces. Step outside and discover your own private retreat—a secluded backyard oasis featuring an in-ground, heated saltwater pool, ideal for summer entertaining or relaxing evenings at home. This historic property has been beautifully preserved while thoughtfully updated, including a brand new roof in 2025, giving you peace of mind without sacrificing its original charm. A rare opportunity to own a true architectural treasure in the heart of Staunton—where history, character, and modern luxury come together in one unforgettable home. Homes like this don’t come around often… and once they’re gone, they’re gone.

116 W Henry St, Staunton
$1,700,000
17 Beds ⋅ 16 Baths ⋅ 25079200 MLS ⋅ ACTIVE Status
Come see this Landmark Estate, Bed and Breakfast, and Wedding Venue with cottages that has ties to Mark Twain. Step into over 150 years of American history at the Garth Woodside Mansion, an extraordinary 36-acre Victorian estate just outside historic downtown Hannibal. This is one of Hannibal’s most prominent properties with a historical tie to Samuel Clemens (better known as Mark Twain)—this mansion stands as both a testament to 19th-century craftsmanship and a cherished link to one of America’s greatest literary figures. Mark Twain was a frequent guest of the Garth family and often stayed in what is now known as the Mark Twain Room, where original furnishings from his visits remain. The Garths and the Clemens family shared a long personal friendship that began in Hannibal’s early river town days, and this home served as a quiet retreat for Twain during his returns to his beloved hometown. Owning this estate means preserving a piece of American literature’s living history—one of the few residences directly tied to Twain that remains privately owned. This Victorian mansion and additional cottages sit on approximately. 36 acres of manicured lawns, rolling pastures, and wooded privacy. This expansive 17 total-bedrooms on the property, most have a private ensuite bathrooms. The wrap-around veranda overlooking scenic Missouri countryside is exquisite. Original features include hand-carved walnut woodwork, marble fireplaces, original light fixtures, and most of the home’s original furnishings. Every room tells a story—from the grand staircase that has welcomed dignitaries and travelers for generations, to the Mark Twain Suite where guests still feel the echo of his wit and worldliness. The mansion’s architecture and furnishings remain remarkably authentic, while modern comforts have been seamlessly integrated. Garth Woodside Mansion is not just a home—it’s a living chapter of American history, where every detail whispers the story of friendship, craftsmanship, and literary legacy. Long operated as a high-end bed & breakfast and wedding venue with additional cottages, the Garth Woodside Mansion has earned consistent acclaim for its historic charm, fine dining experiences, and quiet elegance. This is a turn-key hospitality business opportunity with international name recognition. The property could easily transition into a private residence, corporate retreat, family compound, or heritage investment property. This is a rare offering for private ownership —heritage of this caliber seldom becomes available with the additional income from the cottages as well. Serious and qualified buyers are invited to request private showings and access to records, revenue details, and preservation available on request.

11069 New London Gravel Rd, Hannibal
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